Dr Mubeen Goolam
Research in the Goolam lab focuses on using stem cells to model development and disease in culture. At the Neuroscience Institute we are making use of a novel model system, cerebral organoids, also known as 'mini-brains in a dish', which are generated using human pluripotent stem cells to investigate human brain development and neurodevelopmental disorders in vitro. Developing the first African-specific cerebral organoids will generate a critical experimental resource to study development of the human brain with a focus on the specific environmental and genetic factors prevalent in Sub-Saharan Africa and will be a powerful tool to investigate when brain development goes wrong.
Developmental Neuroscience • Molecular & Cellular Neuroscience • Neurogenetics